The outdoor units will have specs of how much space required around them. I don't think N, S, E, W will have a big impact so go with wherever it will be least annoying athestically and acousticly (e.g. don't put next to bedroom window), and factor in pipe runs. Are you having an unvented cylinder for hot water? I would go with a plant room (large cupboard) to house UVC, UFH manifold and controls