My last self build was a timber I-beam portal frame, structure as follows:-
Plasterboard and skim
350mm Steico timber I-beam, fully filled with Icynene
15mm OSB3 square edge racking
Protect TF200 membrane
50mm timber battens fully filled with Rockwool RW6
Protect A1 membrane
50mm counter battens vented air gap
15mm cedar cladding
The walls and roof were both constructed in a similar way. The construction was successfully tested using the Glaser method for condensation risk. A WUFI analysis was not carried out. That may be of some use.