Is to have a sufficiently large enough heater. The walls in our place are 600mm to 700mm thick stone and when we first moved in we had our 30kW oil fired Aga heating on all the time, in the Spring, to dry it out and warm it up. The house didn't feel comfortable for a long time as the heat was drying the fabric of the building. @SteamyTea explained how much energy is required to do this, and it was substantial. We now have a house that is 23C all the time. You can warm the house up, but it requires a lot of constant expensive heating to do so, and it has to be maintained. Trying to heat one room for a few hours, in your type of house, is pointless.