We used it in a few places but didn't tile directly onto it.
One thing I'd suggest thinking about his how porous it is. I don't know what adhesive you plan to use, but I'd guess it would suck a lot of water out of, say, flexible cementitious adhesives.
All speculation on my part, so please don't rely on it!
Yeah, it's so much more challenging to work with than plasterboard. However, once up, it's dead solid, and you can hang just about anything off it.