Thanks for your reply, I understand that adjusting temps will be slow but it will hopefully just be on all the time at a set temp.
Upstairs has been added as a just in case. Like you say, there is a good chance that it wont be needed except in the bathrooms but as least its there.
Good point, I will change the spacing to 150mm in the bathrooms/ensuites.
I have kept the loops per room in case in the future room temp control was wanted in stead of the open system.
It is actually one manifold upstairs and two down. They are all shown on each diagram so I have 22 loops and three manifolds.
Ill have a look and see if I can reduce the number of loops a bit.
The Gym has heating just in case it is used for something else later. I will isolate that.