After my last ask, we've negotiated with the neighbours to redirect their boiler flue so we can put the MVHR in the most logical place: the garage. I've also compromised by putting upstairs ducting in the cold loft. This has simplified things:
A few notes (or skip to the calculations below)
Upstairs
I've compromised by putting ducts in the cold loft outside the thermal envelope, as my wife is 100% against any boxing in
The loft is well ventilated at all eaves (